Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390633 | 0.79 | RAB9A (0.41) | KMT2ASMN1; SMN2RAB9AHPGDTSHR | |
| SCHEMBL5101428 | 0.76 | KMT2A (0.36) | KMT2ASMN1; SMN2RAB9ANPC1HPGD | |
| Dimethylamine SCHEMBL5095643 | 0.75 | PTPN1 (0.39) | KMT2ASMN1; SMN2RAB9AHPGDTSHR | |
| SCHEMBL5094647 | 0.74 | HTR6 (0.44) | KMT2ASMN1; SMN2NPC1MEN1POLB | |
| SCHEMBL28395634 | 0.73 | TACR1 (0.51) | KMT2ASMN1; SMN2RAB9AHPGDTSHR | |
| SCHEMBL28888717 | 0.69 | MAT2A (0.41) | KMT2AHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL28888365 | 0.69 | TACR1 (0.41) | KMT2AMEN1ATMALDH1A1MAPT | |
| SCHEMBL5089911 | 0.69 | HTR6 (0.44) | KMT2ASMN1; SMN2NPC1HPGDTSHR | |
| SCHEMBL5089797 | 0.69 | HTR6 (0.41) | POLBLMNAMAPT | |
| SCHEMBL5095541 | 0.68 | HTR6 (0.40) | KMT2AHPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556320-B | Method for synthesizing 6H-isoindolo [2,1-a ] indol-6-one derivative | 复旦大学 | 2020-05-12 | — | — | CN | disclosed |