Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396386 | 0.89 | MAPT (0.40) | RAB9ALMNAHSD17B10NPC1HTT | |
| SCHEMBL28420648 | 0.88 | ALDH1A1 (0.45) | RAB9ALMNANPC1ALDH1A1KDM4E | |
| SCHEMBL28261354 | 0.87 | TP53 (0.33) | RAB9ALMNAHSD17B10NPC1HTT | |
| SCHEMBL28261357 | 0.78 | KDR (0.34) | LMNATP53ALDH1A1HPGDMAPK1 | |
| SCHEMBL28867050 | 0.77 | CD274 (0.37) | LMNAALDH1A1KDM4EMAPTGAA | |
| SCHEMBL28419971 | 0.75 | MAPT (0.44) | RAB9ANPC1HTTTP53ALDH1A1 | |
| SCHEMBL28261326 | 0.75 | MAPT (0.32) | ALDH1A1MAPTGAA | |
| SCHEMBL28426457 | 0.72 | CHRNB2 (0.43) | LMNATSHRALDH1A1POLBGAA | |
| SCHEMBL28259961 | 0.71 | MEN1 (0.47) | LMNAHTTTSHRTP53ALDH1A1 | |
| SCHEMBL27972279 | 0.71 | FADS1 (0.39) | RAB9ALMNAHSD17B10NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066724-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-04-17 | — | — | CN | disclosed |