Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | PNLIP | P16233 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972549 | 0.87 | SMO (0.53) | SMOLMNAMEN1KMT2ANPC1 | |
| SCHEMBL28427586 | 0.87 | JAK2 (0.52) | KMT2ANPC1RAB9AJAK2TP53 | |
| SCHEMBL28429490 | 0.84 | NR1H4 (0.45) | SMOMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28426457 | 0.84 | CHRNB2 (0.43) | SMOLMNAMEN1KMT2ACHRNB2 | |
| SCHEMBL27972308 | 0.83 | MEN1 (0.50) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28261342 | 0.83 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9AJAK2 | |
| SCHEMBL27972568 | 0.83 | MEN1 (0.53) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28279915 | 0.83 | MEN1 (0.49) | SMOMEN1KMT2ACHRNB2CHRNB4 | |
| SCHEMBL28419689 | 0.81 | CHRNB2 (0.38) | SMOLMNAMEN1KMT2ACHRNB2 | |
| SCHEMBL27972572 | 0.81 | RAB9A (0.53) | LMNAMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-108863959-A | P2X4 RECEPTOR ANTAGONIST | 日本化学药品株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-104066724-A | P2X4 receptor antagonists | NIPPON CHEMIPHAR CO | 2014-09-24 | — | — | CN | disclosed |