Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810310 | 0.92 | ADORA2B (0.38) | ADORA2BADORA2AALDH1A1TSHRBRD4 | |
| SCHEMBL2670126 | 0.92 | ALDH1A1 (0.39) | ADORA2BADORA2AALDH1A1TSHRBRD4 | |
| SCHEMBL5560844 | 0.92 | ALDH1A1 (0.37) | ADORA2BADORA2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL20211769 | 0.90 | TSHR (0.36) | ADORA2BADORA2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL19810212 | 0.90 | ALDH1A1 (0.38) | ADORA2BADORA2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL28391210 | 0.90 | PRNP (0.36) | ADORA2BADORA2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL28888591 | 0.90 | PSD (0.38) | ADORA2BADORA2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL19810320 | 0.90 | LTB4R (0.36) | ADORA2BADORA2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL25781925 | 0.89 | ADORA2B (0.35) | ADORA2BADORA2AALDH1A1TSHRBRD4 | |
| SCHEMBL28385399 | 0.88 | ALDH1A1 (0.36) | ADORA2BADORA2AALDH1A1TSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116594-B | C-6 modified NanoLuc analogue and preparation method and application thereof | 山东大学 | 2021-05-28 | — | — | CN | claimed |
| CN-111116594-B | C-6 modified NanoLuc analogue and preparation method and application thereof | 山东大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-111116594-A | C-6 modified NanoLuc analogue and preparation method and application thereof | 山东大学 | 2020-05-08 | — | — | CN | disclosed |