Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP14 | P50281 | 2/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945763 | 0.81 | ALDH1A1 (0.69) | KMT2AALDH1A1MAPTKDM4EGAA | |
| SCHEMBL7669940 | 0.81 | MMP2 (0.55) | MMP2MMP14ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL1200801 | 0.80 | ALDH1A1 (0.75) | MMP2MMP14ADAMTS4MMP13ADAMTS5 | |
| SCHEMBL26212911 | 0.79 | L3MBTL1 (0.56) | L3MBTL1MMP2MMP14ALDH1A1MMP1 | |
| SCHEMBL3684870 | 0.79 | CA12 (0.58) | L3MBTL1MMP2MMP14LMNAALDH1A1 | |
| SCHEMBL4519542 | 0.79 | HTT (0.71) | L3MBTL1KMT2AMMP2MMP14LMNA | |
| Trifluoroacetic Acid SCHEMBL8444765 | 0.79 | MMP9 (0.64) | MMP2MMP14ADAMTS4MMP13LMNA | |
| SCHEMBL2947860 | 0.79 | LMNA (0.82) | KMT2ALMNAALDH1A1TBXA2RMAPT | |
| SCHEMBL4517737 | 0.78 | ALDH1A1 (0.68) | L3MBTL1LMNAALDH1A1CTDSP1KDM4E | |
| SCHEMBL3286523 | 0.77 | MMP9 (0.75) | MMP2MMP14ADAMTS4MMP13LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903185-B | Preparation and application of novel eEF2K inhibitor | 四川大学 | 2020-05-26 | — | — | CN | disclosed |