SCHEMBL28401248

SCHEMBL28401248

CCc1ccc(C)c(C(=O)OC(=O)c2cc(CC)ccc2C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.43
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
TRPA1 O75762 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 4/20 0.39
MAPT P10636 3/20 0.39
ALOX15 P16050 2/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 3/20 0.38
TP53 P04637 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
METAP2 P50579 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
AGTR1 P30556 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28401250 0.89 LMNA (0.42) PKMALDH1A1TSHRMAPTGAA
SCHEMBL28398709 0.87 CNR1 (0.42) CYP4F2CYP4A11MAPTMAPK1L3MBTL1
SCHEMBL15999757 0.87 ALDH1A1 (0.53) PKMCYP4F2CYP4A11ALDH1A1TSHR
SCHEMBL19396237 0.85 MEN1 (0.43) PKMCYP4F2CYP4A11TRPA1GABRA1
SCHEMBL28399319 0.84 KAT8 (0.48) PKMALDH1A1TSHRMAPTALOX15
SCHEMBL13652492 0.82 ALDH1A1 (0.50) PKMTRPA1ALDH1A1KDM4EMETAP2
SCHEMBL28407162 0.82 TRPA1 (0.42) CYP4F2CYP4A11TRPA1GABRA1GABRB2
SCHEMBL4678087 0.82 TRPA1 (0.42) PKMCYP4F2CYP4A11TRPA1GABRA1
SCHEMBL28404030 0.82 GABRA1 (0.42) GABRA1GABRB2TSHRMAPTALOX15
SCHEMBL22198613 0.81 PKM (0.39) PKMCYP4F2CYP4A11TRPA1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN claimed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN claimed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN disclosed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN disclosed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed