Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2840134 | 0.87 | KIF11 (0.46) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2835142 | 0.80 | KIF11 (0.45) | KIF11KCNH2 | |
| SCHEMBL2835140 | 0.78 | KIF11 (0.53) | KIF11 | |
| SCHEMBL28746473 | 0.71 | LMNA (0.46) | FAAH | |
| SCHEMBL34261 | 0.71 | KIF11 (0.56) | KIF11 | |
| SCHEMBL17189279 | 0.70 | KIF11 (0.53) | KIF11KCNH2 | |
| SCHEMBL27608746 | 0.70 | KIF11 (0.78) | KIF11 | |
| SCHEMBL4397129 | 0.70 | KIF11 (0.78) | KIF11 | |
| SCHEMBL8035494 | 0.70 | CYP4F2 (0.51) | FAAH | |
| SCHEMBL8741783 | 0.69 | KIF11 (0.41) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228012-A1 | PENDANT FATTY ACID IMAGING AGENTS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-09-09 | — | — | US | disclosed |
| US-7556794-B2 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070128119-A1 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | disclosed |
| US-7179444-B2 | Pendant fatty acid imaging agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1490114-A1 | PENDANT FATTY ACID IMAGING AGENTS | Biostream, Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040081616-A1 | Pendant fatty acid imaging agents | BIOSTREAM, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2003084575-A1 | PENDANT FATTY ACID IMAGING AGENTS | BIOSTREAM, INC. (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128119-A1 | Pendant fatty acid imaging agents | FABP3, CPT1B, FABP1 | KIF11 1443/4885FAAH 54/4885HDAC3 2343/4885 |
| US-20100228012-A1 | PENDANT FATTY ACID IMAGING AGENTS | FABP3, CPT1B, FABP1 | KIF11 1443/4885FAAH 54/4885HDAC3 2343/4885 |
| US-20040081616-A1 | Pendant fatty acid imaging agents | FABP3, CPT1B, FABP1 | KIF11 1443/4885FAAH 54/4885HDAC3 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.