Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL31339251 | 0.82 | KDM4E (0.40) | BBOX1KDM4EEPHX2ALDH1A1MAPT | |
| Methacrylic Acid SCHEMBL28476094 | 0.82 | TDP1 (0.33) | ALDH1A1 | |
| SCHEMBL27457112 | 0.82 | TDP1 (0.48) | BBOX1KDM4EEPHX2ALDH1A1MAPT | |
| SCHEMBL6670491 | 0.82 | EPHX2 (0.33) | BBOX1KDM4EEPHX2ALDH1A1MAPT | |
| Methacrylic Acid SCHEMBL27893258 | 0.81 | EPHX2 (0.50) | EPHX2ALDH1A1 | |
| Potassium Ion SCHEMBL2786192 | 0.79 | — | — | |
| Methacrylic Acid SCHEMBL1368368 | 0.78 | PTGS1 (0.33) | EPHX2 | |
| Methacrylic Acid SCHEMBL28305261 | 0.77 | PTGS1 (0.32) | EPHX2 | |
| Methacrylic Acid SCHEMBL27979557 | 0.77 | PTGS1 (0.32) | EPHX2 | |
| Methacrylic Acid SCHEMBL27962788 | 0.77 | PTGS1 (0.32) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217792-A | Preparation method of super-hydrophilic material and durable wetting gradient surface | 西北工业大学 | 2023-06-06 | — | — | CN | claimed |
| CN-106117862-B | Detect Br2Colloidal crystal sensor, preparation method and application thereof | 青岛大学 | 2020-05-12 | — | — | CN | claimed |
| CN-116217792-A | Preparation method of super-hydrophilic material and durable wetting gradient surface | 西北工业大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-116217792-A | Preparation method of super-hydrophilic material and durable wetting gradient surface | 西北工业大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-112899054-B | Graphene-polymer nano composite water-based lubricating additive and preparation method and application thereof | 西北师范大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-112899054-A | Graphene-polymer nano composite water-based lubricating additive and preparation method and application thereof | 西北师范大学 | 2021-06-04 | — | — | CN | disclosed |