Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672469 | 0.79 | ABCB1 (0.65) | PDE4ACYP2C8KDM4EABCB1SMN1; SMN2 | |
| SCHEMBL16011311 | 0.78 | ABCB1 (0.66) | PDE4ACYP2C8KDM4EABCB1SMN1; SMN2 | |
| SCHEMBL28409862 | 0.75 | PDE4A (0.54) | PDE4ACYP2C8KDM4EABCB1SMN1; SMN2 | |
| SCHEMBL28409481 | 0.75 | PDE4A (0.54) | PDE4ACYP2C8KDM4EABCB1SMN1; SMN2 | |
| SCHEMBL20147031 | 0.75 | CALCRL (0.74) | PDE4AABCB1MEN1KMT2AABCG2 | |
| SCHEMBL10903343 | 0.74 | PDGFRB (0.49) | PDE4ACYP2C8KDM4ESMN1; SMN2MAPT | |
| SCHEMBL4002247 | 0.72 | APP (0.61) | PDE4ACYP2C8KDM4EABCB1SMN1; SMN2 | |
| SCHEMBL30461597 | 0.72 | CYP2A6 (0.47) | KDM4ESMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL21860285 | 0.71 | ALOX5 (0.52) | PDE4ACYP2C8KDM4EABCB1SMN1; SMN2 | |
| SCHEMBL7159656 | 0.70 | PDGFRB (0.68) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107325067-B | Mulberry octyl element M derivative of phosphodiesterase 4 inhibitor and application thereof | 广州中医药大学 | 2020-05-12 | — | — | CN | claimed |
| CN-107325067-B | Mulberry octyl element M derivative of phosphodiesterase 4 inhibitor and application thereof | 广州中医药大学 | 2020-05-12 | — | — | CN | disclosed |