SCHEMBL2840970

SCHEMBL2840970

CCCCC/C=C\C/C=C\CCCCCCCCOC[C@H](CN1CCCC1)OCCCCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
LPAR1 Q92633 2/20 0.43
LPAR3 Q9UBY5 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3490523 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL2840040 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL3488076 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL2841053 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL3490529 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL3238670 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL2879443 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL19617734 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL16371200 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3
SCHEMBL3487909 1.00 ALDH1A1 (0.53) ALDH1A1CNR1CNR2LPAR1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100104629-A1 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2010-04-29 US claimed
US-20100099738-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-04-22 US claimed
WO-2010030739-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-18 WO claimed
WO-2010030730-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-18 WO claimed
US-20100063135-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-11 US claimed
WO-2009129395-A1 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2009-10-22 WO claimed
US-11633365-B2 Nucleic acid-containing lipid nanoparticle KYOWA KIRIN CO., LTD. (JP) 2023-04-25 US disclosed
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE KYOWA KIRIN CO., LTD. (JP) 2020-11-26 US disclosed
EP-3662913-A1 NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES Kyowa Kirin Co., Ltd. (JP) 2020-06-10 EP disclosed
US-20100104629-A1 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2010-04-29 US disclosed
US-20100099738-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-04-22 US disclosed
WO-2010030739-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-18 WO disclosed
WO-2010030730-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-18 WO disclosed
US-20100063135-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-11 US disclosed
WO-2009129395-A1 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2009-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099738-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF LIPA, LIPG, LIPC ALDH1A1 1734/4885CNR1 3492/4885CNR2 3231/4885
US-20100104629-A1 CATIONIC LIPIDS AND USES THEREOF LIPA, SGMS2, SGMS1 ALDH1A1 4724/4885CNR1 3144/4885CNR2 2239/4885
US-20100063135-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF LIPA, LIPG, LIPC ALDH1A1 1734/4885CNR1 3492/4885CNR2 3231/4885
US-11633365-B2 Nucleic acid-containing lipid nanoparticle LIPA, LIPC, PNLIP ALDH1A1 354/4885CNR1 3755/4885CNR2 3991/4885
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE LIPA, LIPC, PNLIP ALDH1A1 354/4885CNR1 3755/4885CNR2 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.