Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044498 | 0.87 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL25136437 | 0.80 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL28410129 | 0.78 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL7009282 | 0.76 | PIK3CA (0.48) | SMN1; SMN2KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL21971567 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1MAPTGAATSHR | |
| SCHEMBL14653301 | 0.74 | ATM (0.42) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25136290 | 0.74 | WNT1 (0.37) | MAPTHPGD | |
| SCHEMBL7016486 | 0.74 | MEN1 (0.51) | NPC1RAB9ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL22469863 | 0.73 | GABRP (0.40) | KDM4EPARP1ALDH1A1L3MBTL1 | |
| SCHEMBL13306946 | 0.73 | MAPT (0.43) | SMN1; SMN2KDM4ENPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320651-B | Chiral amino-pyridine-phosphine tridentate ligand, manganese complex, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-01-17 | — | — | CN | disclosed |
| CN-111320651-A | Chiral amino-pyridine-phosphine tridentate ligand, manganese complex, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2020-06-23 | — | — | CN | disclosed |