Acetophenone

Acetophenone

SCHEMBL28410239

CC(=O)c1ccccc1.CCOC=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
MAPT P10636 5/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAOB P27338 2/20 0.45
ALDH1A1 P00352 4/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HPGD P15428 2/20 0.43
KMT2A Q03164 4/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
NPC1 O15118 3/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RAB9A P51151 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL27911468 0.87 TSHR (0.54) LMNAMAPTALDH1A1KMT2ACES2
Benzophenone SCHEMBL27578794 0.87 ALDH1A1 (0.54) LMNAMAPTSMN1; SMN2ALDH1A1HTT
Benzil SCHEMBL28893812 0.87 CES2 (0.54) LMNAMAPTALDH1A1HPGDCES2
Benzoyl Peroxide SCHEMBL27983972 0.84 LMNA (0.61) LMNAMAPTSMN1; SMN2ALDH1A1KMT2A
Ethoxycarbonyl Group SCHEMBL28306644 0.84 SMN1; SMN2 (0.41) LMNAMAPTSMN1; SMN2ALDH1A1HPGD
4-Hydroxyacetophenone SCHEMBL28289945 0.84 HSD17B1 (0.55) LMNAMAPTSMN1; SMN2MAOBALDH1A1
Methyl Benzoate SCHEMBL28054188 0.82 TSHR (0.66) LMNAMAPTSMN1; SMN2ALDH1A1L3MBTL1
Methyl 4-Pyridylketone SCHEMBL28024697 0.82 KMT2A (0.46) LMNAMAPTSMN1; SMN2ALDH1A1HTT
Acetophenone SCHEMBL8054903 0.80 MAPT (0.54) LMNAMAPTSMN1; SMN2MAOBALDH1A1
Acetophenone SCHEMBL27469600 0.80 SMN1; SMN2 (0.54) LMNAMAPTSMN1; SMN2MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293491-B Method for removing acyl from diazo salt of aryl 中南大学 2020-06-23 CN disclosed