Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | DPYD | Q12882 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952293 | 0.77 | ALDH1A1 (0.50) | ATAD2ALDH1A1DPYDMEN1KMT2A | |
| SCHEMBL11616697 | 0.75 | ATAD2 (0.50) | ATAD2ALDH1A1HAO1NOTUMHTR1A | |
| SCHEMBL11617247 | 0.73 | IDO1 (0.50) | ATAD2IDO1ALDH1A1NOTUMHTR1A | |
| SCHEMBL576094 | 0.73 | ACHE (0.53) | IDO1ALDH1A1HAO1NOTUMHTR1A | |
| SCHEMBL28412020 | 0.71 | TYMS (0.44) | ALDH1A1HAO1DPYD | |
| Hydrogen Sulfide SCHEMBL11580912 | 0.71 | HTR1A (0.50) | IDO1ALDH1A1HAO1NOTUMHTR1A | |
| SCHEMBL15906499 | 0.71 | HTR1A (0.50) | IDO1ALDH1A1HAO1NOTUMHTR1A | |
| Phosphine SCHEMBL29157942 | 0.71 | HTR1A (0.50) | IDO1ALDH1A1HAO1NOTUMHTR1A | |
| SCHEMBL29031117 | 0.71 | HTR1A (0.55) | IDO1ALDH1A1HAO1NOTUMHTR1A | |
| SCHEMBL3557794 | 0.70 | ALDH1A1 (0.59) | ATAD2ALDH1A1NOTUMDPYDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651267-B | Method for preparing 5-sulfur/selenium modified uracil derivative | 中国科学院化学研究所 | 2020-05-19 | — | — | CN | disclosed |