Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.38 |
| ▸ | LPL | P06858 | 6/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28417409 | 0.82 | LIPG (0.39) | LIPGLPLTRPV1MGLLPTGS2 | |
| Methyl Alcohol SCHEMBL28415177 | 0.81 | LIPG (0.40) | LIPGLPLTRPV1MGLLPTGS2 | |
| Methyl Alcohol SCHEMBL28422938 | 0.78 | ALOX5 (0.41) | LIPGLPLPTGS2CNR2 | |
| SCHEMBL29066831 | 0.75 | KAT2B (0.36) | PTGS2CYP3A4TSHR | |
| SCHEMBL22193304 | 0.74 | PTGS2 (0.37) | PTGS2CYP3A4TSHR | |
| SCHEMBL21173190 | 0.68 | TSHR (0.37) | TSHR | |
| SCHEMBL28415336 | 0.66 | TAS1R3 (0.30) | — | |
| SCHEMBL29951913 | 0.66 | LIPG (0.46) | LIPGLPLTRPV1MGLLCYP3A4 | |
| Methyl Alcohol SCHEMBL28643482 | 0.66 | LIPG (0.54) | LIPGLPLTRPV1MGLLPTGS2 | |
| SCHEMBL12098018 | 0.65 | LIPG (0.47) | LIPGLPLTRPV1MGLLPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356695-B | Novel tricyclic compounds | 北京加科思新药研发有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-111356695-A | Novel tricyclic compounds | 北京加科思图新药研发有限公司 | 2020-06-30 | — | — | CN | disclosed |