Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.39 |
| ▸ | LPL | P06858 | 6/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28415177 | 0.82 | LIPG (0.40) | LIPGLPLTRPV1MGLLPTGS2 | |
| Methyl Alcohol SCHEMBL28415337 | 0.82 | LIPG (0.38) | LIPGLPLTRPV1MGLLPTGS2 | |
| Methyl Alcohol SCHEMBL28422938 | 0.80 | ALOX5 (0.41) | LIPGLPLPTGS2CNR2 | |
| SCHEMBL21064318 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL3788053 | 0.67 | MGLL (0.34) | LIPGLPLMGLL | |
| SCHEMBL29951913 | 0.67 | LIPG (0.46) | LIPGLPLTRPV1MGLLCYP3A4 | |
| SCHEMBL22342658 | 0.67 | HIF1A (0.38) | PTGS2 | |
| SCHEMBL12098018 | 0.66 | LIPG (0.47) | LIPGLPLTRPV1MGLLPTGS2 | |
| SCHEMBL12269065 | 0.65 | LPL (0.50) | LIPGLPLTRPV1MGLL | |
| SCHEMBL793134 | 0.64 | LIPG (0.50) | LIPGLPLTRPV1MGLLPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356695-B | Novel tricyclic compounds | 北京加科思新药研发有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-111356695-A | Novel tricyclic compounds | 北京加科思图新药研发有限公司 | 2020-06-30 | — | — | CN | disclosed |