SCHEMBL28419013

SCHEMBL28419013

C=CCC1C=CC=CN1Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
GAA P10253 2/20 0.33
MAPK1 P28482 1/20 0.33
CTNNB1 P35222 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP19A1 P11511 1/20 0.33
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SIGMAR1 Q99720 2/20 0.32
F2 P00734 1/20 0.31
PLG P00747 1/20 0.31
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31
CMA1 P23946 1/20 0.31
CTRC Q99895 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
KDM4E B2RXH2 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
EHMT2 Q96KQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306536 0.82 SIGMAR1 (0.34) ALDH1A1SMN1; SMN2CYP19A1LMNANPSR1
SCHEMBL27507721 0.73 SIGMAR1 (0.38) ALDH1A1SMN1; SMN2CYP19A1LMNASIGMAR1
Hydrochloric Acid SCHEMBL27547946 0.73
Bromide SCHEMBL28038390 0.73
SCHEMBL5610169 0.71 SIGMAR1 (0.36) ALDH1A1SMN1; SMN2CYP19A1SIGMAR1F2
SCHEMBL27515932 0.71 ACHE (0.41) ALDH1A1LMNANPSR1SIGMAR1F2
SCHEMBL30672032 0.71 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2LMNANPSR1SIGMAR1
Hydrochloric Acid SCHEMBL28350609 0.70 ACHE (0.40) ALDH1A1LMNANPSR1SIGMAR1F2
Bromide SCHEMBL27410484 0.70 SIGMAR1 (0.35) ALDH1A1SMN1; SMN2CYP19A1SIGMAR1F2
SCHEMBL28656106 0.70 CYP19A1 (0.36) ALDH1A1SMN1; SMN2CYP19A1LMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111315718-B Molecules having one hydrophobic group and two identical hydrophilic ionic groups and compositions thereof 埃科莱布美国股份有限公司 2024-02-20 CN disclosed
CN-111315718-A Molecules having one hydrophobic group and two identical hydrophilic ionic groups and compositions thereof 埃科莱布美国股份有限公司 2020-06-19 CN disclosed