SCHEMBL9306536

SCHEMBL9306536

C=CC1C=CC=CN1Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
ALDH1A1 P00352 3/20 0.34
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
F2 P00734 1/20 0.33
PLG P00747 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33
CMA1 P23946 1/20 0.33
CTRC Q99895 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
CYP19A1 P11511 1/20 0.32
CALM1 P0DP23 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FUCA1 P04066 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30672032 0.85 ALDH1A1 (0.40) SIGMAR1ALDH1A1LMNANPSR1F2
SCHEMBL28419013 0.82 ALDH1A1 (0.33) SIGMAR1ALDH1A1LMNANPSR1F2
SCHEMBL27507721 0.77 SIGMAR1 (0.38) SIGMAR1ALDH1A1LMNAF2PLG
SCHEMBL27515932 0.75 ACHE (0.41) SIGMAR1ALDH1A1LMNANPSR1F2
SCHEMBL5610169 0.75 SIGMAR1 (0.36) SIGMAR1ALDH1A1F2PLGELANE
SCHEMBL28656106 0.74 CYP19A1 (0.36) SIGMAR1ALDH1A1LMNAF2PLG
Hydrochloric Acid SCHEMBL28350609 0.74 ACHE (0.40) SIGMAR1ALDH1A1LMNANPSR1F2
Bromide SCHEMBL27410484 0.74 SIGMAR1 (0.35) SIGMAR1ALDH1A1F2PLGELANE
Bromide SCHEMBL27722888 0.74 ACHE (0.40) SIGMAR1ALDH1A1LMNANPSR1F2
Bromide SCHEMBL29099283 0.72 CYP19A1 (0.35) SIGMAR1ALDH1A1LMNAF2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5344891-A Acrylonitrile, quaternization MITSUBISHI RAYON CO., LTD. (JP) 1994-09-06 US disclosed