Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19087155 | 0.81 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15520797 | 0.81 | MAPT (0.62) | CYP19A1CYP11B1CYP11B2ITK | |
| Hydrochloric Acid SCHEMBL21492793 | 0.78 | LOXL2 (0.53) | CYP19A1CYP11B1CYP11B2ITK | |
| SCHEMBL19077891 | 0.78 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2ITK | |
| SCHEMBL272966 | 0.78 | L3MBTL1 (0.62) | CYP19A1 | |
| SCHEMBL28393209 | 0.76 | L3MBTL1 (0.47) | CYP11B1 | |
| SCHEMBL30730357 | 0.76 | HSD17B10 (0.57) | CYP19A1CYP11B1CYP11B2ITK | |
| SCHEMBL28138593 | 0.75 | MEN1 (0.55) | CYP19A1 | |
| SCHEMBL27364042 | 0.75 | KLKB1 (0.54) | CYP19A1CYP11B1CYP11B2ITK | |
| SCHEMBL3261102 | 0.75 | FFAR1 (0.50) | CYP19A1CYP11B1CYP11B2ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432246-B | Heteroaromatic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-07-07 | — | — | CN | disclosed |