⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420979 | 0.84 | POLB (0.36) | — | |
| SCHEMBL30576990 | 0.81 | POLB (0.36) | — | |
| SCHEMBL27007938 | 0.75 | HPGD (0.33) | — | |
| SCHEMBL30788667 | 0.71 | RXRA (0.40) | — | |
| SCHEMBL29644614 | 0.70 | PTPN1 (0.38) | — | |
| SCHEMBL29233400 | 0.68 | PDCD1 (0.38) | — | |
| Phosphine SCHEMBL1505614 | 0.68 | POLB (0.34) | — | |
| SCHEMBL28703141 | 0.66 | ROCK2 (0.38) | — | |
| SCHEMBL30357793 | 0.65 | PTPN1 (0.34) | — | |
| SCHEMBL6096638 | 0.65 | NOTUM (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |