SCHEMBL284240

SCHEMBL284240

O=C(CCCCCCCCCCn1ccnc1)NCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.68
TBXAS1 P24557 5/20 0.63
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
QPCT Q16769 1/20 0.61
ALDH1A1 P00352 1/20 0.57
GAA P10253 1/20 0.56
EPHX2 P34913 1/20 0.56
HPGD P15428 1/20 0.56
TSHR P16473 1/20 0.56
MAPT P10636 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15190312 0.90 HPGD (0.69) SMN1; SMN2MEN1KMT2AQPCTGAA
SCHEMBL9271796 0.84 HPGD (0.78) SMN1; SMN2MEN1KMT2AALDH1A1GAA
SCHEMBL14255017 0.82 TBXAS1 (0.66) SMN1; SMN2TBXAS1MEN1KMT2AQPCT
SCHEMBL14255015 0.82 TBXAS1 (0.66) SMN1; SMN2TBXAS1MEN1KMT2AQPCT
SCHEMBL10247217 0.81 SMN1; SMN2 (0.62) SMN1; SMN2TBXAS1QPCTALDH1A1GAA
Hydrochloric Acid SCHEMBL411425 0.80 SMN1; SMN2 (0.61) SMN1; SMN2TBXAS1QPCTALDH1A1GAA
SCHEMBL10853278 0.80 SMN1; SMN2 (0.68) SMN1; SMN2MEN1KMT2AQPCTALDH1A1
SCHEMBL2942358 0.78 MEN1 (0.96) SMN1; SMN2MEN1KMT2AALDH1A1GAA
SCHEMBL10819292 0.77 SMN1; SMN2 (0.71) SMN1; SMN2MEN1KMT2AQPCTALDH1A1
SCHEMBL77556 0.76 QPCT (1.00) SMN1; SMN2QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4532268-A Imidazole agent for retarding the polymerization of aziridine compounds ESPE, FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1985-07-30 US claimed
EP-3883522-B1 USE OF A POLYETHER-MODIFIED POLYDIMETHYL SILOXANE FOR REDUCING THE STICKINESS OF A DENTAL IMPRESSION COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-01-08 EP disclosed
US-20240285476-A1 DENTAL COMPOSITION COMPRISING AN ISORBIDE COMPONENT SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-08-29 US disclosed
EP-4346741-A1 DENTAL COMPOSITION COMPRISING AN ISORBIDE COMPONENT Solventum Intellectual Properties Company (US) 2024-04-10 EP disclosed
WO-2022248954-A1 DENTAL COMPOSITION COMPRISING AN ISORBIDE COMPONENT 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-01 WO disclosed
EP-3883522-A1 CURABLE COMPOSITION CONTAINING A POLYETHER-MODIFIED POLYDIMETHYL SILOXANE 3M Innovative Properties Company (US) 2021-09-29 EP disclosed
EP-2613754-B1 CURABLE COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2018-10-17 EP disclosed
US-9216141-B2 Curable composition, process of production and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-22 US disclosed
US-20130157226-A1 CURABLE COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-20 US disclosed
EP-2428199-A1 Curable composition, process of production and use thereof 3M Innovative Properties Company (US) 2012-03-14 EP disclosed
EP-0110429-B1 RETARDERS FOR THE POLYMERISATION OF AZIRIDINE COMPOUNDS ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1990-01-17 EP disclosed
US-4532268-A Imidazole agent for retarding the polymerization of aziridine compounds ESPE, FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1985-07-30 US disclosed
EP-0110429-A2 Retarders for the polymerisation of aziridine compounds ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1984-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240285476-A1 DENTAL COMPOSITION COMPRISING AN ISORBIDE COMPONENT INTS9, PUF60, TAS2R42 SMN1; SMN2 3399/4885TBXAS1 3950/4885MEN1 578/4885
US-20130157226-A1 CURABLE COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF LDHA, LDHB, SOD1 SMN1; SMN2 1718/4885TBXAS1 3523/4885MEN1 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.