Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424632 | 1.00 | F2 (0.57) | F2KMT2AMEN1HDAC1SMN1; SMN2 | |
| SCHEMBL9942091 | 0.81 | ATM (0.68) | F2KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL29549847 | 0.75 | PGR (0.77) | KMT2AMEN1HDAC1SMN1; SMN2HTT | |
| SCHEMBL20021987 | 0.75 | PGR (0.77) | KMT2AMEN1HDAC1SMN1; SMN2HTT | |
| SCHEMBL28396503 | 0.75 | PGR (0.77) | KMT2AMEN1HDAC1SMN1; SMN2HTT | |
| SCHEMBL6560346 | 0.75 | KMT2A (0.62) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL1403531 | 0.74 | HDAC1 (0.80) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1403532 | 0.74 | HDAC1 (0.80) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL3258120 | 0.73 | KMT2A (0.68) | KMT2AMEN1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL9616562 | 0.73 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419835-B | Application of benzene sulfonamide compound in preparing medicine for treating diabetes | 徐州医科大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-111419835-A | Application of benzenesulfonamide compound as mPGES-2 inhibitor and medicine | 徐州医科大学 | 2020-07-17 | — | — | CN | disclosed |