Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425936 | 0.87 | SMN1; SMN2 (0.48) | HTTPGRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28425938 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5187428 | 0.78 | PGR (0.64) | HTTTP53PGRBCL2L1MCL1 | |
| SCHEMBL28428561 | 0.76 | CCR8 (0.55) | PGRBCL2L1MCL1LMNAALDH1A1 | |
| SCHEMBL8752398 | 0.73 | ALDH1A1 (0.68) | HTTTP53PGRBCL2L1MCL1 | |
| SCHEMBL5305683 | 0.73 | LMNA (0.66) | HTTTP53PGRLMNAALDH1A1 | |
| SCHEMBL28428653 | 0.72 | MAPT (0.50) | HTTTP53BCL2L1MCL1ALDH1A1 | |
| SCHEMBL4067674 | 0.72 | PGR (0.56) | HTTTP53PGRBCL2L1MCL1 | |
| SCHEMBL28750145 | 0.72 | PGR (0.56) | HTTTP53PGRBCL2L1MCL1 | |
| SCHEMBL7113124 | 0.71 | SMN1; SMN2 (0.59) | TP53PGRLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111056978-B | Sulfonamide compound and preparation method and application thereof | 西安交通大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-111056978-A | Sulfonamide compound and preparation method and application thereof | 西安交通大学 | 2020-04-24 | — | — | CN | disclosed |