Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MMP12 | P39900 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 4/20 | 0.48 |
| ▸ | MMP14 | P50281 | 4/20 | 0.48 |
| ▸ | MMP16 | P51512 | 4/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428561 | 0.91 | CCR8 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28895993 | 0.87 | POLB (0.52) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28425940 | 0.82 | SMN1; SMN2 (0.56) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5187428 | 0.75 | PGR (0.64) | MAPTCCR8POLBTP53BCL2L1 | |
| SCHEMBL28750145 | 0.74 | PGR (0.56) | MAPTCCR8POLBTP53BCL2L1 | |
| SCHEMBL28428545 | 0.72 | HTT (0.46) | MAPTCCR8POLBTP53BCL2L1 | |
| SCHEMBL28169381 | 0.72 | MAPT (0.70) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5898987 | 0.71 | MMP2 (0.76) | MAPTHDAC4HDAC1MMP2MMP8 | |
| SCHEMBL7854504 | 0.71 | KMT2A (0.64) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8752410 | 0.71 | GAA (0.73) | MAPTPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111056978-B | Sulfonamide compound and preparation method and application thereof | 西安交通大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-111056978-A | Sulfonamide compound and preparation method and application thereof | 西安交通大学 | 2020-04-24 | — | — | CN | disclosed |