Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428653 | 0.87 | MAPT (0.50) | POLBMAPTTP53BCL2L1MCL1 | |
| SCHEMBL28428561 | 0.84 | CCR8 (0.55) | BCL2L1MCL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28436226 | 0.81 | ALDH1A1 (0.49) | MAPTALDH1A1KMT2AMEN1ITGA1 | |
| SCHEMBL28432202 | 0.79 | MAPT (0.54) | POLBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28437276 | 0.78 | IDH1 (0.54) | ALDH1A1ITGA1HDAC1HDAC8HDAC3 | |
| SCHEMBL28432982 | 0.76 | ACLY (0.50) | POLBMAPTALDH1A1TSHR | |
| SCHEMBL28438687 | 0.76 | GAA (0.55) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL2500403 | 0.75 | MMP2 (0.53) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL397624 | 0.72 | ALDH1A1 (0.47) | POLBMAPTALDH1A1KMT2AMEN1 | |
| Benzoic Acid SCHEMBL28546974 | 0.72 | TSHR (0.55) | MAPTALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111056978-B | Sulfonamide compound and preparation method and application thereof | 西安交通大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-111056978-A | Sulfonamide compound and preparation method and application thereof | 西安交通大学 | 2020-04-24 | — | — | CN | disclosed |