Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F9 | P00740 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | HAT1 | O14929 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28885915 | 0.80 | NR4A2 (0.50) | GPR84RAB9ANR4A2CREBBPMEN1 | |
| SCHEMBL17912674 | 0.78 | NR4A2 (0.54) | GPR84RAB9ANR4A2CREBBPMEN1 | |
| SCHEMBL10366074 | 0.78 | MAPT (0.52) | GPR84NR4A2CREBBPMEN1MAPT | |
| SCHEMBL21383576 | 0.77 | NR3C1 (0.58) | GPR84RAB9ANR4A2CREBBPMEN1 | |
| SCHEMBL28435403 | 0.76 | SRC (0.43) | RAB9ANR4A2KMT2ASMN1; SMN2LOXL2 | |
| SCHEMBL1972827 | 0.76 | GPR84 (0.59) | GPR84MEN1MAPTPKMKMT2A | |
| SCHEMBL2884867 | 0.74 | GPR84 (0.74) | GPR84RAB9ANR4A2CREBBPMEN1 | |
| SCHEMBL28375303 | 0.74 | GPR84 (0.51) | GPR84RAB9ANR4A2CREBBPMAPT | |
| SCHEMBL30266453 | 0.74 | MEN1 (0.48) | MEN1MAPTPKMKMT2ACTSK | |
| SCHEMBL4099306 | 0.74 | HTR2A (0.54) | GPR84NR4A2CREBBPMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149603-B | Application of indole compounds and derivatives thereof in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-07-14 | — | — | CN | disclosed |