SCHEMBL28429340

SCHEMBL28429340

CC(C)(C)OC(=O)N1CCc2cc(N3CCOCC3)ccc21

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 6/20 0.45
ABHD6 Q9BV23 2/20 0.45
IDH1 O75874 1/20 0.44
USP30 Q70CQ3 1/20 0.44
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PRKDC P78527 1/20 0.42
DHODH Q02127 1/20 0.42
RORC P51449 1/20 0.41
PIK3CA P42336 2/20 0.41
MTOR P42345 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
LGMN Q99538 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30681471 0.88 DRD3 (0.46) GPR119ABHD6USP30DHODHALDH1A1
SCHEMBL8257530 0.86 HTR6 (0.46) GPR119ABHD6DHODH
SCHEMBL15000510 0.80 ESR2 (0.65) GPR119ABHD6IDH1USP30USP2
SCHEMBL1010120 0.80 NR1H2 (0.63) GPR119ABHD6IDH1USP30USP2
SCHEMBL31330650 0.80 ALDH1A1 (0.51) GPR119SMN1; SMN2RORCALDH1A1LMNA
SCHEMBL30681257 0.79 GPR119 (0.46) GPR119DHODH
SCHEMBL8200750 0.78 NOTUM (0.64) GPR119ABHD6DHODHALDH1A1MEN1
SCHEMBL3899182 0.78 ESR2 (0.61) GPR119ABHD6DHODH
SCHEMBL26548171 0.78 RORC (0.54) RORCALDH1A1
SCHEMBL2809581 0.78 ABHD6 (0.67) GPR119ABHD6IDH1USP30USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111471037-B Allylamine compound and application thereof 药捷安康(南京)科技股份有限公司 2023-02-10 CN disclosed
CN-111471037-A Allylamine compound and application thereof 南京药捷安康生物科技有限公司 2020-07-31 CN disclosed