SCHEMBL28437151

SCHEMBL28437151

CCc1ccc(C(C)[Si](OC)(OC)OC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TP53 P04637 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
IDO1 P14902 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP17A1 P05093 1/20 0.34
HPGD P15428 1/20 0.34
CYP2A6 P11509 1/20 0.33
TRPA1 O75762 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235152 0.85 ESR1 (0.36) ESR1ESR2ALDH1A1TRPA1
SCHEMBL926685 0.82 IDO1 (0.33) L3MBTL1IDO1ESR1ESR2
SCHEMBL927038 0.82 IDO1 (0.33) L3MBTL1TSHRIDO1ESR1ESR2
SCHEMBL927436 0.82 IDO1 (0.33) L3MBTL1TSHRMAPK1ATMTDP1
SCHEMBL28756796 0.79 PTGS2 (0.39) L3MBTL1TSHRMAPK1TDP1TP53
SCHEMBL27147585 0.79 CYP17A1 (0.34) TP53ESR1ESR2AKR1C2CYP17A1
Hydrochloric Acid SCHEMBL18529434 0.78 KDM4E (0.42) TDP1IDO1ESR1ESR2ALDH1A1
SCHEMBL13417845 0.78 KMT2A (0.33) TAAR1IDO1ESR1ESR2ALDH1A1
SCHEMBL927010 0.77 ESR1 (0.35) TDP1ESR1ESR2LMNA
SCHEMBL927622 0.77 LMNA (0.31) TDP1ESR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118765339-A Synthesis, capping and dispersion of high refractive index nanocrystals and nanocomposite materials PT SPE塞博康有限责任公司 2024-10-11 CN claimed
CN-118063670-A Solvent-free formulation and nanocomposite 皮瑟莱根特科技有限责任公司 2024-05-24 CN claimed
CN-117916299-A Zirconia and titania formulations and nanocomposites for nanoimprint lithography PT SPE塞博康有限责任公司 2024-04-19 CN claimed
CN-113316609-B Solvent-free formulation and nanocomposite 皮瑟莱根特科技有限责任公司 2024-03-08 CN claimed
CN-113316609-A Solvent-free formulations and nanocomposites 皮瑟莱根特科技有限责任公司 2021-08-27 CN claimed
CN-118765339-A Synthesis, capping and dispersion of high refractive index nanocrystals and nanocomposite materials PT SPE塞博康有限责任公司 2024-10-11 CN disclosed
CN-118063670-A Solvent-free formulation and nanocomposite 皮瑟莱根特科技有限责任公司 2024-05-24 CN disclosed
CN-117916299-A Zirconia and titania formulations and nanocomposites for nanoimprint lithography PT SPE塞博康有限责任公司 2024-04-19 CN disclosed
CN-113316609-B Solvent-free formulation and nanocomposite 皮瑟莱根特科技有限责任公司 2024-03-08 CN disclosed
CN-114341281-A Curable ink composition, cured product, and nanocomposite material 东京应化工业株式会社 2022-04-12 CN disclosed
CN-113316609-A Solvent-free formulations and nanocomposites 皮瑟莱根特科技有限责任公司 2021-08-27 CN disclosed
CN-113227463-A Synthesis, capping and dispersion of TiO2 nanocrystals 皮瑟莱根特科技有限责任公司 2021-08-06 CN disclosed
CN-111466037-A Light emitting device with improved light outcoupling 科迪华公司 2020-07-28 CN disclosed