Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235152 | 0.79 | ESR1 (0.36) | ALDH1A1ESR1ESR2 | |
| SCHEMBL28437151 | 0.78 | L3MBTL1 (0.44) | ALDH1A1TDP1IDO1ESR1ESR2 | |
| SCHEMBL927436 | 0.77 | IDO1 (0.33) | TDP1IDO1ESR1ESR2 | |
| SCHEMBL926685 | 0.77 | IDO1 (0.33) | IDO1ESR1ESR2 | |
| SCHEMBL927038 | 0.77 | IDO1 (0.33) | ALDH1A1IDO1ESR1ESR2 | |
| SCHEMBL16187132 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1TDP1CHRNB2CHRNA4 | |
| SCHEMBL27147585 | 0.73 | CYP17A1 (0.34) | ESR1ESR2 | |
| SCHEMBL13417845 | 0.72 | KMT2A (0.33) | ALDH1A1IDO1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL4795693 | 0.72 | ALDH1A1 (0.74) | KDM4EALDH1A1TDP1CHRNB2CHRNA4 | |
| SCHEMBL330049 | 0.71 | CYP3A4 (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368592-B1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW TORAY CO LTD (JP) | 2025-12-03 | — | — | EP | claimed |
| US-20250127174-A1 | FORMULATIONS FOR ANTIMICROBIAL THERMOSET COATINGS | CORNING INCORPORATED | 2025-04-24 | — | — | US | claimed |
| US-10605957-B2 | Gas permeable ophthalmic lens material and gas permeable ophthalmic lens of such material | ScienBiziP Consulting(Shenzhen)Co., Ltd. (CN) | 2020-03-31 | — | — | US | claimed |
| US-12630697-B2 | Polyaminosiloxane water tree repellant for electrical insulation | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-05-19 | — | — | US | disclosed |
| EP-3368592-B1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW TORAY CO LTD (JP) | 2025-12-03 | — | — | EP | disclosed |
| US-12440821-B2 | Method for tracing subterranean formations with oil-soluble organic molecular tracers and extracting them of from oil phases | SAUDI ARABIAN OIL COMPANY (SA) | 2025-10-14 | — | — | US | disclosed |
| US-20250127174-A1 | FORMULATIONS FOR ANTIMICROBIAL THERMOSET COATINGS | CORNING INCORPORATED | 2025-04-24 | — | — | US | disclosed |
| US-20250127174-A1 | FORMULATIONS FOR ANTIMICROBIAL THERMOSET COATINGS | CORNING INCORPORATED | 2025-04-24 | — | — | US | disclosed |
| US-20230407063-A1 | Polyaminosiloxane Water Tree Repellant for Electrical Insulation | DOW SILICONES CORPORATION | 2023-12-21 | — | — | US | disclosed |
| CN-116507675-A | Polyaminosiloxane water-proof treeing agent for electric insulation | 陶氏环球技术有限责任公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20230182110-A1 | METHOD AND MATERIALS FOR EXTRACTION OF OIL-SOLUBLE ORGANIC MOLECULAR TRACERS FROM OIL PHASES | SAUDI ARABIAN OIL COMPANY (SA) | 2023-06-15 | — | — | US | disclosed |
| US-20190015302-A1 | FLUORESCENT PARTICULATE MATERIAL | L'OREAL (FR) | 2019-01-17 | — | — | US | disclosed |
| US-20180326395-A1 | CATIONIC COMPOSITE SILICATE FILTER AIDS | IMERYS USA, INC. | 2018-11-15 | — | — | US | disclosed |
| EP-3397718-A1 | FLUORESCENT PARTICULATE MATERIAL | L'Oréal (FR) | 2018-11-07 | — | — | EP | disclosed |
| EP-3377191-A1 | CATIONIC COMPOSITE SILICATE FILTER AIDS | Imerys Filtration Minerals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-3368592-A1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | Dow Corning Toray Co., Ltd. (JP) | 2018-09-05 | — | — | EP | disclosed |
| US-20180235207-A1 | PESTICIDE RETENTION COATING COMPOSITIONS AND USES THEREOF | INTEGRICOTE, INC. (US) | 2018-08-23 | — | — | US | disclosed |
| WO-2017114877-A1 | FLUORESCENT PARTICULATE MATERIAL | L'OREAL (FR) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017073755-A1 | COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN | DOW CORNING TORAY CO., LTD. (JP) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017031289-A1 | PESTICIDE RETENTION COATING COMPOSITIONS AND USES THEREOF | INTEGRICOTE, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10605957-B2 | Gas permeable ophthalmic lens material and gas permeable ophthalmic lens of such material | EPCAM, CRYAA, VIM | CHRM2 498/4885CHRM1 657/4885KDM4E 4080/4885 |
| US-20180235207-A1 | PESTICIDE RETENTION COATING COMPOSITIONS AND USES THEREOF | DDT, ACHE, CAPG | CHRM2 21/4885CHRM1 77/4885KDM4E 1401/4885 |
| US-20190015302-A1 | FLUORESCENT PARTICULATE MATERIAL | HNRNPM, NPM1, HNRNPF | CHRM2 213/4885CHRM1 86/4885KDM4E 4493/4885 |
| US-12630697-B2 | Polyaminosiloxane water tree repellant for electrical insulation | PYM1, SCO2, AQP1 | CHRM2 243/4885CHRM1 170/4885KDM4E 2167/4885 |
| US-20250127174-A1 | FORMULATIONS FOR ANTIMICROBIAL THERMOSET COATINGS | CTRC, CDC37, CMBL | CHRM2 3330/4885CHRM1 2786/4885KDM4E 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.