Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435566 | 0.82 | KDM4E (0.44) | LMNAGAAHPGDMEN1KMT2A | |
| SCHEMBL28444097 | 0.82 | PIM1 (0.46) | LMNACYP1A2HPGDMEN1KMT2A | |
| SCHEMBL29956275 | 0.82 | LMNA (0.57) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL14068343 | 0.82 | LMNA (0.49) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL1336656 | 0.77 | KIF11 (0.46) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL29953769 | 0.77 | KIF11 (0.46) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL20842851 | 0.76 | LMNA (0.43) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL20094583 | 0.76 | LMNA (0.43) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL22898794 | 0.74 | LMNA (0.51) | LMNAGAACYP1A2HPGDCA12 | |
| SCHEMBL29363428 | 0.74 | LMNA (0.51) | LMNAGAACYP1A2HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107377-A1 | PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL | KARANICOLAS JOHN (US) | 2026-05-21 | — | — | WO | disclosed |
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | disclosed |