SCHEMBL29953769

SCHEMBL29953769

O=Cc1[nH]c2ccccc2c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.46
MAPT P10636 5/20 0.46
NPSR1 Q6W5P4 2/20 0.46
HKDC1 Q2TB90 1/20 0.46
ALDH1A1 P00352 5/20 0.44
GPR3 P46089 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 5/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 2/20 0.43
GLA P06280 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP1A2 P05177 2/20 0.41
TNKS2 Q9H2K2 2/20 0.41
CYP2C19 P33261 1/20 0.41
CYP2A6 P11509 1/20 0.41
IMPDH2 P12268 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336656 1.00 KIF11 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL24492924 0.80 ALDH1A1 (0.44) MAPTALDH1A1GPR3HSD17B10KDM4E
SCHEMBL28136136 0.78 AHR (0.49) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL28437263 0.77 LMNA (0.51) MAPTNPSR1ALDH1A1HSD17B10KDM4E
SCHEMBL29954183 0.76 KIF11 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL1163942 0.76 MAPT (0.55) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL4730473 0.76 KIF11 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL29956558 0.76 AHR (0.55) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL1254486 0.76 AHR (0.55) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL29031413 0.76 ALDH1A1 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107377-A1 PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL KARANICOLAS JOHN (US) 2026-05-21 WO disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed