Sugi Predict

Sugi Predict / Compounds / SCHEMBL1336656

SCHEMBL1336656

SCHEMBL1336656

O=Cc1[nH]c2ccccc2c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 2/20 0.46
▸ MAPT P10636 5/20 0.46
▸ NPSR1 Q6W5P4 2/20 0.46
▸ HKDC1 Q2TB90 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.44
▸ GPR3 P46089 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ KDM4E B2RXH2 5/20 0.43
▸ LMNA P02545 2/20 0.43
▸ GAA P10253 2/20 0.43
▸ GLA P06280 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ CYP1A2 P05177 2/20 0.41
▸ TNKS2 Q9H2K2 2/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ CYP2A6 P11509 1/20 0.41
▸ IMPDH2 P12268 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953769 1.00 KIF11 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL24492924 0.80 ALDH1A1 (0.44) MAPTALDH1A1GPR3HSD17B10KDM4E
SCHEMBL28136136 0.78 AHR (0.49) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL28437263 0.77 LMNA (0.51) MAPTNPSR1ALDH1A1HSD17B10KDM4E
SCHEMBL29954183 0.76 KIF11 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL1163942 0.76 MAPT (0.55) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL4730473 0.76 KIF11 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL29956558 0.76 AHR (0.55) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL1254486 0.76 AHR (0.55) KIF11MAPTNPSR1HKDC1ALDH1A1
SCHEMBL29031413 0.76 ALDH1A1 (0.46) KIF11MAPTNPSR1HKDC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101665522-B Metallocene compound and preparation method and application thereof PETROCHINA CO LTD 2011-10-05 — — CN claimed
CN-101205235-B Metal complex as well as preparation method and uses thereof CHINESE ACAD INST CHEMISTRY 2011-10-05 — — CN claimed
CN-101665522-A Metallocene compound and preparation method and application thereof PETROCHINA CO LTD 2010-03-10 — — CN claimed
CN-101205235-A Metal complex as well as preparation method and uses thereof CHINESE ACAD INST CHEMISTRY (CN) 2008-06-25 — — CN claimed
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 — — CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 — — CN disclosed
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS Kinoxis Therapeutics Pty Ltd (AU) 2024-02-29 — — US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 — — CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 — — WO disclosed
CN-106928121-B High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound 暨南大学 2020-05-12 — — CN disclosed
CN-106061969-B TRPA1 regulator ALGOMEDIX, INC. (US) 2019-10-29 — — CN disclosed
CN-101665522-B Metallocene compound and preparation method and application thereof PETROCHINA CO LTD 2011-10-05 — — CN disclosed
US-20110124674-A1 5/5-OR 5/6-MEMBERED CONDENSED RING CYCLOALKYLAMINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2011-05-26 — — US disclosed
US-20110124674-A1 5/5-OR 5/6-MEMBERED CONDENSED RING CYCLOALKYLAMINE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2011-05-26 — — US disclosed
EP-2319841-A1 (5-MEMBERED)-(5-MEMBERED) OR (5-MEMBERED)-(6-MEMBERED) FUSED RING CYCLOALKYLAMINE DERIVATIVE MSD K.K. (JP) 2011-05-11 — — EP disclosed
EP-2319841-A1 (5-MEMBERED)-(5-MEMBERED) OR (5-MEMBERED)-(6-MEMBERED) FUSED RING CYCLOALKYLAMINE DERIVATIVE MSD K.K. (JP) 2011-05-11 — — EP disclosed
CN-101665522-A Metallocene compound and preparation method and application thereof PETROCHINA CO LTD 2010-03-10 — — CN disclosed
WO-2010013595-A1 (5-MEMBERED)-(5-MEMBERED) OR (5-MEMBERED)-(6-MEMBERED) FUSED RING CYCLOALKYLAMINE DERIVATIVE 萬有製薬株式会社 (JP) 2010-02-04 — — WO disclosed
CN-101205235-A Metal complex as well as preparation method and uses thereof CHINESE ACAD INST CHEMISTRY (CN) 2008-06-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 KIF11 4444/4885MAPT 3388/4885NPSR1 4430/4885
US-20110124674-A1 5/5-OR 5/6-MEMBERED CONDENSED RING CYCLOALKYLAMINE DERIVATIVE MCHR1, MC5R, MCHR2 KIF11 2511/4885MAPT 2883/4885NPSR1 82/4885
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS OXTR, AVPR1B, AVPR1A KIF11 3285/4885MAPT 380/4885NPSR1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.