Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL28439126 | 0.97 | THRB (0.39) | THRBCA4FAHD1 | |
| SCHEMBL28440379 | 0.94 | THRB (0.43) | THRBCA4FAHD1 | |
| SCHEMBL11776372 | 0.94 | THRB (0.43) | THRBCA4FAHD1 | |
| Lithium Ion SCHEMBL29779553 | 0.94 | THRB (0.43) | THRB | |
| Potassium Ion SCHEMBL2234663 | 0.92 | THRB (0.56) | THRB | |
| Potassium Ion SCHEMBL2790789 | 0.92 | THRB (0.56) | THRB | |
| Potassium Ion SCHEMBL2196710 | 0.92 | THRB (0.56) | THRB | |
| Potassium Ion SCHEMBL1905877 | 0.92 | THRB (0.56) | THRB | |
| Potassium Ion SCHEMBL31098404 | 0.92 | THRB (0.56) | THRB | |
| Potassium Ion SCHEMBL5066664 | 0.92 | THRB (0.56) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333499-B | Process for producing fluorine-containing carboxylic acid | 中蓝晨光化工研究设计院有限公司 | 2023-02-10 | — | — | CN | disclosed |
| CN-111333499-A | Process for producing fluorine-containing carboxylic acid | 中蓝晨光化工研究设计院有限公司 | 2020-06-26 | — | — | CN | disclosed |