SCHEMBL28438546

SCHEMBL28438546

NC(=O)c1ccc(N)cc1.OC1(O)C=CC=C(c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 4/20 0.39
CYP2C19 P33261 3/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP3A4 P08684 2/20 0.39
POLB P06746 1/20 0.39
PARP1 P09874 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MKNK1 Q9BUB5 3/20 0.38
MKNK2 Q9HBH9 2/20 0.38
CHEK2 O96017 1/20 0.36
PLA2G10 O15496 1/20 0.36
PLA2G2A P14555 1/20 0.36
NPC1 O15118 2/20 0.34
CYP1A2 P05177 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957775 0.81 HDAC1 (0.37) NPC1RAB9AALDH1A1LMNAHPGD
Methane SCHEMBL28875106 0.80 HDAC1 (0.36) NPC1RAB9AALDH1A1LMNAHPGD
Biphenyl SCHEMBL28602112 0.74 CYP3A4 (0.62) PARP10CYP2C19HSD17B10CYP3A4POLB
SCHEMBL4002907 0.73 LMNA (0.33) CYP2C19HSD17B10CYP3A4POLBPARP1
SCHEMBL6849682 0.72 CYP3A4 (0.31) HSD17B10CYP3A4TDP1ALDH1A1TP53
Aniline SCHEMBL28319061 0.71 TSHR (0.68) PARP10CYP2C19HSD17B10CYP3A4POLB
Benzene SCHEMBL6865184 0.71 PARP10 (0.68) PARP10CYP2C19HSD17B10CYP3A4POLB
Benzene SCHEMBL28558933 0.71 PARP10 (0.68) PARP10CYP2C19HSD17B10CYP3A4POLB
Hydrochloric Acid SCHEMBL5072257 0.70 HDAC1 (0.34) NPC1RAB9AHDAC1
SCHEMBL10872336 0.70 SRR (0.33) CYP2C19HSD17B10CYP3A4POLBPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113302227-B Composition, metal insulating coating material, and method for producing same 三菱化学株式会社 2024-04-26 CN disclosed
CN-113383029-A Ester compound, resin composition, cured product, and laminated film 积水化学工业株式会社 2021-09-10 CN disclosed
CN-113302227-A Composition and metal insulating coating material 三菱化学株式会社 2021-08-24 CN disclosed
CN-112368287-A Tetracarboxylic dianhydride, polyimide precursor resin, polyimide precursor resin solution, polyimide solution, and polyimide film 引能仕株式会社 2021-02-12 CN disclosed
CN-112272664-A Tetracarboxylic dianhydride, carbonyl compound, polyimide precursor resin, and polyimide 引能仕株式会社 2021-01-26 CN disclosed
CN-111936555-A Resin, resin precursor, and resin precursor solution 引能仕株式会社 2020-11-13 CN disclosed
CN-111742012-A Polyimide precursor resin composition 引能仕株式会社 2020-10-02 CN disclosed
CN-108885920-B Resin composition 三菱化学株式会社 2020-08-07 CN disclosed