Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 4/20 | 0.51 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860500 | 0.77 | HSD17B14 (0.52) | HSD17B14CNR2HDAC8HDAC1HDAC6 | |
| SCHEMBL28605670 | 0.75 | CNR2 (0.62) | CNR2HDAC8MEN1KMT2AMGAM | |
| SCHEMBL28443611 | 0.75 | MGAM (0.61) | CNR2HDAC8MEN1KMT2AMGAM | |
| SCHEMBL11316978 | 0.72 | CNR2 (0.69) | CNR2HDAC8MEN1KMT2AMGAM | |
| SCHEMBL8746411 | 0.72 | CNR2 (0.47) | HSD17B14CNR2HDAC8MEN1KMT2A | |
| SCHEMBL22501419 | 0.71 | RAB9A (0.50) | HSD17B14CNR2HDAC8HDAC6MGAM | |
| SCHEMBL3862153 | 0.71 | RAB9A (0.48) | HSD17B14CNR2MEN1KMT2AMGAM | |
| SCHEMBL8521342 | 0.69 | CNR2 (0.44) | CNR2HDAC8MGAMNPC1RAB9A | |
| SCHEMBL9335143 | 0.69 | CNR2 (0.48) | HSD17B14CNR2HDAC8MEN1KMT2A | |
| SCHEMBL9585344 | 0.69 | ALOX5 (0.48) | CNR2KMT2AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111494381-A | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2020-08-07 | — | — | CN | disclosed |