Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24139907 | 0.88 | NCF1 (0.34) | NCF1 | |
| SCHEMBL1268659 | 0.80 | CYP1A2 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL20374563 | 0.75 | SIGMAR1 (0.37) | CHRM2CHRM1CHRM3SIGMAR1 | |
| SCHEMBL17889254 | 0.75 | CHRM3 (0.31) | NCF1CHRM3 | |
| SCHEMBL41970 | 0.75 | NCF1 (0.65) | NCF1ENPP1CHRM2CHRM1CHRM3 | |
| SCHEMBL18714964 | 0.73 | L3MBTL1 (0.41) | NCF1 | |
| SCHEMBL22475301 | 0.73 | ALOX5 (0.34) | NCF1CHRM3 | |
| SCHEMBL5667084 | 0.72 | NCF1 (0.37) | NCF1ENPP1CHRM2CHRM1CHRM3 | |
| SCHEMBL3642423 | 0.71 | HTT (0.39) | NCF1ENPP1CHRM2CHRM1CHRM3 | |
| SCHEMBL103162 | 0.71 | SMN1; SMN2 (0.45) | NCF1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286174-B | Substituted 2,4- (1H,3H) pyrimidinedione as PARP inhibitor and application thereof | 上海勋和医药科技有限公司 | 2020-08-18 | — | — | CN | disclosed |