SCHEMBL284443

SCHEMBL284443

CCCCC(CC)COC(=O)C(C)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 4/20 0.46
CA2 P00918 2/20 0.46
LMNA P02545 4/20 0.45
TSHR P16473 4/20 0.45
ATM Q13315 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.43
GAA P10253 2/20 0.43
XBP1 P17861 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.42
RECQL P46063 2/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
NR5A2 O00482 1/20 0.35
NR5A1 Q13285 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284593 0.93 ALDH1A1 (0.43) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL490318 0.87 ATM (0.54) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL490531 0.85 LMNA (0.52) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL2952892 0.83 ALDH1A1 (0.42) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL9845247 0.83 ALDH1A1 (0.44) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL490662 0.83 ALDH1A1 (0.51) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL12201039 0.82 ALDH1A1 (0.58) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL490492 0.82 ALDH1A1 (0.48) ALDH1A1CYP3A4CA2LMNATSHR
SCHEMBL28115084 0.82 ESR1 (0.44) ALDH1A1LMNAATML3MBTL1GAA
SCHEMBL9674260 0.81 ALDH1A1 (0.44) ALDH1A1CYP3A4CA2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230376-A1 HEAT SOURCE MACHINE, OPERATION METHOD OF THE SAME, AND REFRIGERATING MACHINE OIL FOR HEAT SOURCE MACHINE MITSUBISHI HEAVY INDUSTRIES THERMAL SYSTEMS, LTD. (JP) 2025-07-17 US disclosed
WO-2023136068-A1 HEAT SOURCE MACHINE, OPERATION METHOD THEREFOR, AND REFRIGERATION OIL FOR HEAT SOURCE MACHINE 三菱重工サーマルシステムズ株式会社 2023-07-20 WO disclosed
CN-107532834-B Refrigerant circulation device and refrigerant circulation method 三菱重工制冷空调系统株式会社 2020-06-19 CN disclosed
EP-2428553-B1 Lubricating oil composition NIPPON OIL CORP (JP) 2013-05-22 EP disclosed
US-8299006-B2 Compressor oil composition NIPPON OIL CORPORATION (JP) 2012-10-30 US disclosed
US-8268293-B2 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives MERCK PATENT GMBH (DE) 2012-09-18 US disclosed
US-8247360-B2 Heat treating oil composition NIPPON OIL CORPORATION (JP) 2012-08-21 US disclosed
US-8236740-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2012-08-07 US disclosed
US-8232233-B2 Lubricating oil composition for machine tools NIPPON OIL CORPORATION (JP) 2012-07-31 US disclosed
US-8227387-B2 Metalworking oil composition NIPPON OIL CORPORATION (JP) 2012-07-24 US disclosed
US-20120053096-A1 Lubricating oil composition for machine tools NIPPON OIL CORPORATION 2012-03-01 US disclosed
EP-2423298-A1 Compressor oil composition Nippon Oil Corporation (JP) 2012-02-29 EP disclosed
EP-2423297-A1 Hydraulic oil composition Nippon Oil Corporation (JP) 2012-02-29 EP disclosed
EP-2423296-A1 Lubricating oil composition for machine tools Nippon Oil Corporation (JP) 2012-02-29 EP disclosed
US-20120046205-A1 Compressor oil composition NIPPON OIL CORPORATION 2012-02-23 US disclosed
US-8106233-B2 Applying di-2-ethylhexyl 4-hydroxy-3,5-dimethoxy-benzylmalonate; protective action against UV rays, oxidative stress on body cells, counters skin ageing MERCK PATENT GMBH (DE) 2012-01-31 US disclosed
US-20100093568-A1 REFRIGERATOR OIL, COMPRESSOR OIL COMPOSITION, HYDRAULIC FLUID COMPOSITION, METALWORKING FLUID COMPOSITION, HEAT TREATMENT OIL COMPOSITION, LUBRICANT COMPOSITION FOR MACHINE TOOL AND LUBRICANT COMPOSITION NIPPON OIL CORPORATION (JP) 2010-04-15 US disclosed
EP-2039746-A1 REFRIGERATOR OIL, COMPRESSOR OIL COMPOSITION, HYDRAULIC FLUID COMPOSITION, METALWORKING FLUID COMPOSITION, HEAT TREATMENT OIL COMPOSITION, LUBRICANT COMPOSITION FOR MACHINE TOOL AND LUBRICANT COMPOSITION Nippon Oil Corporation (JP) 2009-03-25 EP disclosed
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives MERCK PATENT GMBH (DE) 2008-07-17 US disclosed
US-20080152603-A1 Antioxidants SUSONITY Commercial GmbH (DE) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080152603-A1 Antioxidants GPX4, GPX1, CAT ALDH1A1 181/4885CYP3A4 392/4885CA2 1558/4885
US-20080171004-A1 Using compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, such as 4-hydroxyphenylpropionic acid, or 2-ethylhexyl 4-hydroxy-3,5-dimethoxycinnamate, or polysiloxanes which contain benzylidenemalonic acid derivatives HPD, HAAO, UGT1A6 ALDH1A1 314/4885CYP3A4 63/4885CA2 2547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.