Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451959 | 0.81 | HTR2C (0.41) | HTR2CMCHR1CYP2B6SMN1; SMN2TP53 | |
| SCHEMBL7520140 | 0.79 | KMT2A (0.43) | CYP2A6CYP2B6LMNAALOX15SMN1; SMN2 | |
| SCHEMBL9536321 | 0.77 | ALDH1A1 (0.49) | HTR2BCYP2B6LMNATSHRHIF1A | |
| SCHEMBL7522441 | 0.76 | RAB9A (0.53) | CYP2B6TSHRRAB9AMAPK1NPSR1 | |
| SCHEMBL9093485 | 0.74 | ALDH1A1 (0.39) | MTNR1AHTR1A | |
| SCHEMBL28439711 | 0.74 | KDM4E (0.32) | HTR2BHTR2CNPSR1 | |
| SCHEMBL9093838 | 0.73 | GRIN2B (0.41) | HTR1A | |
| SCHEMBL30629208 | 0.73 | CYP2B6 (0.38) | MTNR1ACYP2B6 | |
| SCHEMBL9093465 | 0.73 | GRIN2B (0.42) | MTNR1AHTR1A | |
| SCHEMBL28042771 | 0.72 | KMT2A (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417396-A | Methods of treating cancer with small molecule NF-kB inhibitors | 免疫目标公司 | 2020-07-14 | — | — | CN | disclosed |