Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680346 | 0.80 | BACE1 (0.52) | BACE1HSD17B10ALDH1A1HPGDBCL2L1 | |
| SCHEMBL16429040 | 0.80 | BACE1 (0.56) | BACE1TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL23174685 | 0.75 | ESR1 (0.52) | — | |
| SCHEMBL28454387 | 0.75 | HSD17B1 (0.35) | HSD17B10ALDH1A1HPGDCYP3A4CYP2C19 | |
| SCHEMBL1243947 | 0.73 | ALDH1A1 (0.52) | HSD17B10ALDH1A1HPGDLMNAALOX15 | |
| SCHEMBL28445611 | 0.73 | TSHR (0.41) | TSHRHSD17B10 | |
| SCHEMBL23174684 | 0.73 | ALOX15 (0.46) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL136305 | 0.73 | BACE1 (0.56) | BACE1HSD17B10ALDH1A1HPGDBCL2L1 | |
| SCHEMBL3418225 | 0.73 | BACE1 (0.56) | BACE1HSD17B10ALDH1A1HPGDBCL2L1 | |
| SCHEMBL7916383 | 0.73 | BACE1 (0.56) | BACE1HSD17B10ALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105929642-B | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member | 佳能株式会社 | 2020-09-01 | — | — | CN | disclosed |