Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477982 | 1.00 | MAOA (0.33) | MAOAMAOBMIFMEN1KMT2A | |
| SCHEMBL30477989 | 0.88 | MAOA (0.33) | MAOAMAOBMIFMEN1KMT2A | |
| SCHEMBL28449321 | 0.88 | MAOA (0.33) | MAOAMAOBMIFMEN1KMT2A | |
| SCHEMBL30477992 | 0.84 | MAOA (0.37) | MAOAMAOBMIFMEN1KMT2A | |
| SCHEMBL28456875 | 0.84 | MAOA (0.37) | MAOAMAOBMIFMEN1KMT2A | |
| SCHEMBL30477990 | 0.78 | GABRP (0.36) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL28451137 | 0.78 | GABRP (0.36) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL30477993 | 0.70 | TDP2 (0.43) | MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL28897988 | 0.70 | TDP2 (0.43) | MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6209822 | 0.69 | MAOA (0.43) | MAOAMAOBMIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533764-B | Method for preparing siloxyindene derivative by utilizing domino reaction | 杭州师范大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-111533764-A | Method for preparing siloxyindene derivative by using domino reaction | 杭州师范大学 | 2020-08-14 | — | — | CN | disclosed |