Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823338 | 0.73 | HTT (0.51) | HTTTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL1870579 | 0.73 | HTT (0.51) | HTTTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL29823485 | 0.69 | TSHR (0.56) | HTTTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL1875194 | 0.69 | TSHR (0.56) | HTTTSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL30225577 | 0.66 | KMT2A (0.68) | HTTL3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL14931741 | 0.66 | KMT2A (0.68) | HTTL3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL25376426 | 0.65 | ALDH1A1 (0.60) | HTTL3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL11367933 | 0.64 | SIGMAR1 (0.46) | L3MBTL1ACHEBACE1KMT2AMEN1 | |
| SCHEMBL7016109 | 0.63 | VCP (0.57) | VCPSMN1; SMN2NPC1CYP1A2CYP3A4 | |
| SCHEMBL13321381 | 0.62 | VCP (0.49) | TSHRL3MBTL1VCPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302287-A | Methods for hematopoietic stem and progenitor cell transplantation therapy | 美真达治疗公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-111902411-A | Compositions and methods for expanding hematopoietic stem and progenitor cells and treating inherited metabolic disorders | 美真达治疗公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111712262-A | Dosing regimens for mobilizing hematopoietic stem and progenitor cells | 美真达治疗公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111683669-A | Compositions and methods for hematopoietic stem and progenitor cell transplantation therapy | 美真达治疗公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111542597-A | Compositions and methods for expanding hematopoietic stem and progenitor cells | 美真达治疗公司 | 2020-08-14 | — | — | CN | disclosed |