Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | BACE1 | P56817 | 5/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371638 | 0.82 | ACHE (0.68) | SIGMAR1ACHEBACE1BCHEKMT2A | |
| SCHEMBL4034085 | 0.79 | SIGMAR1 (0.54) | SIGMAR1ACHEBACE1BCHEKMT2A | |
| SCHEMBL13888612 | 0.76 | ACHE (0.52) | SIGMAR1ACHEBACE1BCHEKMT2A | |
| SCHEMBL662711 | 0.73 | MAOA (0.57) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL11386928 | 0.73 | CXCR4 (0.57) | SIGMAR1KMT2ACXCR4MEN1POLB | |
| SCHEMBL13321381 | 0.73 | VCP (0.49) | SIGMAR1L3MBTL1HTR1DHTR1B | |
| SCHEMBL13669690 | 0.73 | VCP (0.49) | SIGMAR1ACHEBACE1BCHEDRD4 | |
| SCHEMBL11381943 | 0.72 | KMT2A (0.49) | ACHEBACE1BCHEKMT2ACXCR4 | |
| Hydrochloric Acid SCHEMBL4799055 | 0.72 | MAOA (0.55) | KMT2AMEN1 | |
| SCHEMBL31706160 | 0.70 | MAOA (0.54) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |