Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24514891 | 0.59 | — | — | |
| SCHEMBL24448995 | 0.57 | — | — | |
| SCHEMBL28223750 | 0.42 | — | — | |
| SCHEMBL25204735 | 0.39 | — | — | |
| SCHEMBL23908691 | 0.39 | — | — | |
| SCHEMBL31703723 | 0.39 | — | — | |
| Cyclooctane SCHEMBL23152619 | 0.32 | — | — | |
| Water SCHEMBL20503800 | 0.32 | — | — | |
| Water SCHEMBL4407393 | 0.32 | — | — | |
| SCHEMBL20636614 | 0.32 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636946-A | Preparation method and application of metal-organic framework material with high exposed active sites | 河南师范大学 | 2023-01-24 | — | — | CN | claimed |
| CN-114195124-B | Porous carbon material, preparation method thereof and application thereof in sodium battery | 山东大学 | 2023-01-17 | — | — | CN | claimed |
| CN-114195124-A | Porous carbon material, preparation method thereof and application thereof in sodium battery | 山东大学 | 2022-03-18 | — | — | CN | claimed |
| CN-111574722-A | Photoconductive metal organic framework thin film material, preparation method and application thereof | 中国科学院福建物质结构研究所 | 2020-08-25 | — | — | CN | claimed |
| CN-115636946-A | Preparation method and application of metal-organic framework material with high exposed active sites | 河南师范大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-112259902-B | Six-arm branched polymeric ionic liquid gel electrolyte diaphragm and preparation method thereof | 南京理工大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-114976015-A | Two-dimensional metal organic framework based composite electrode material, and preparation method and application thereof | 巢湖学院 | 2022-08-30 | — | — | CN | disclosed |
| CN-113244961-B | Bimetallic CoCu-MOF visible light catalyst and preparation method and application thereof | 上海师范大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111574722-B | Photoconductive metal organic framework thin film material, preparation method and application thereof | 中国科学院福建物质结构研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-113540351-A | Field-effect transistor, gas sensor and manufacturing method thereof | 丰田自动车株式会社 | 2021-10-22 | — | — | CN | disclosed |
| CN-113244961-A | Bimetallic CoCu-MOF visible light catalyst and preparation method and application thereof | 上海师范大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-112259902-A | Six-arm branched polymeric ionic liquid gel electrolyte diaphragm and preparation method thereof | 南京理工大学 | 2021-01-22 | — | — | CN | disclosed |