SCHEMBL28449185

SCHEMBL28449185

CCOP(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 1/20 0.48
CA14 Q9ULX7 1/20 0.48
NR1I2 O75469 1/20 0.42
ACHE P22303 1/20 0.41
IDO1 P14902 2/20 0.40
TDP1 Q9NUW8 3/20 0.39
MAPK1 P28482 2/20 0.39
GAA P10253 3/20 0.39
MAPT P10636 3/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28442330 0.83 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL8939010 0.83 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL8638207 0.82 NFE2L2 (0.44) GAAMAPTKDM4ENPC1RAB9A
SCHEMBL28441397 0.82 CA12 (0.42) CA1CA2CA7CA9CA12
SCHEMBL10706891 0.79 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL13992853 0.79 CA12 (0.44) CA1CA2CA7CA9CA12
SCHEMBL28452610 0.79 NR5A1 (0.41) CA1CA2CA7CA9CA12
SCHEMBL10709571 0.77 ACHE (0.38) CA1CA2CA7CA9ACHE
Bromide SCHEMBL28448855 0.76 CA12 (0.41) CA1CA2CA7CA9CA12
SCHEMBL8939002 0.76 CA4 (0.47) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-119504845-A Method for preparing S- (4- (2, 2-diaryl vinyl) thio-butyl) selenium/tellurium phosphorus/phosphonate 湖南理工学院 2025-02-25 CN disclosed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN disclosed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN disclosed