Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356626 | 0.87 | ACHE (0.39) | NFE2L2MAOBPOLBPTGS1MAPT | |
| SCHEMBL7776013 | 0.87 | ACHE (0.39) | NFE2L2MAOBPOLBPTGS1MAPT | |
| SCHEMBL30775610 | 0.86 | ACHE (0.35) | NFE2L2KDM4EPOLBPTGS1SMN1; SMN2 | |
| SCHEMBL28449185 | 0.82 | CA1 (0.48) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8637790 | 0.76 | NFE2L2 (0.50) | NFE2L2RELAALDH1A1KDM4EMAOB | |
| SCHEMBL30775608 | 0.74 | L3MBTL1 (0.40) | NFE2L2ALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7778608 | 0.73 | TDP1 (0.36) | KDM4EMAOBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30356619 | 0.70 | ACHE (0.44) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL196443 | 0.69 | CYP3A4 (0.39) | RELAALDH1A1L3MBTL1TP53 | |
| SCHEMBL28442330 | 0.69 | CA1 (0.44) | ALDH1A1KDM4EL3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | claimed |
| US-5756848-A | Process for preparing secondary arylphosphine oxides | HOECHST AKTIENGESELLSCHAFT | 1998-05-26 | — | — | US | disclosed |