Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451395 | 0.82 | METAP1 (0.40) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28456875 | 0.81 | MAOA (0.37) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL30477992 | 0.81 | MAOA (0.37) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28447042 | 0.81 | HSP90AA1 (0.33) | ALDH1A1MAPTHPGD | |
| SCHEMBL28451512 | 0.80 | METAP1 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2MAOB | |
| SCHEMBL30477979 | 0.80 | METAP1 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2MAOB | |
| SCHEMBL30477977 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28451556 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL30477993 | 0.79 | TDP2 (0.43) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL30477983 | 0.78 | METAP1 (0.39) | ALDH1A1MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533764-B | Method for preparing siloxyindene derivative by utilizing domino reaction | 杭州师范大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-111533764-A | Method for preparing siloxyindene derivative by using domino reaction | 杭州师范大学 | 2020-08-14 | — | — | CN | disclosed |