Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of 2,3-Dihydroxybenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,3-Dihydroxybenzoic Acid SCHEMBL30315474 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL2033960 | 0.95 | KDM4E (0.68) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL19953770 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL31178719 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL30940445 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL10388912 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL2831364 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL3980948 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL31148351 | 0.95 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ETERTALOX5 | |
| Potassium Ion SCHEMBL5319305 | 0.84 | SELL (0.60) | ALDH1A1HPGDKDM4ETERTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479913-B | Compositions containing lanthanide metal complexes | 罗地亚经营管理公司 | 2021-12-21 | — | — | CN | claimed |
| CN-111479913-A | Compositions containing lanthanide metal complexes | 罗地亚经营管理公司 | 2020-07-31 | — | — | CN | claimed |