Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978954 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7982076 | 0.78 | ALDH1A1 (0.51) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL28453095 | 0.73 | AGBL2 (0.39) | AGBL2L3MBTL1HTT | |
| SCHEMBL7526392 | 0.72 | S100A4 (0.56) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7982504 | 0.72 | TSHR (0.42) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7985347 | 0.71 | NPC1 (0.51) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7985647 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL741752 | 0.71 | NPSR1 (0.64) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL12272679 | 0.69 | L3MBTL1 (0.52) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL2090244 | 0.69 | NPSR1 (0.47) | ALDH1A1TSHRMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |