Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 5/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622262 | 0.98 | DHODH (0.55) | KMODHODHEGFRHDAC8RXRA | |
| SCHEMBL12070646 | 0.98 | KMO (0.57) | KMODHODHEGFRHDAC8RXRA | |
| SCHEMBL27843569 | 0.89 | KMO (0.56) | KMODHODHHDAC8RXRARXRB | |
| SCHEMBL22064857 | 0.87 | EGFR (0.60) | KMODHODHEGFRRXRARXRB | |
| SCHEMBL8060297 | 0.83 | ALDH1A1 (0.36) | KMODHODHRXRARXRBATM | |
| SCHEMBL699008 | 0.83 | KMO (0.67) | KMODHODHHDAC8RXRARXRB | |
| SCHEMBL30698052 | 0.83 | KMO (0.67) | KMODHODHHDAC8RXRARXRB | |
| SCHEMBL28462472 | 0.82 | DHODH (0.75) | KMODHODHEGFRHDAC8RXRA | |
| Biphenyl SCHEMBL505047 | 0.81 | RAB9A (0.52) | KMOHDAC8MAPTSMN1; SMN2TDP1 | |
| Hydrogen Sulfide SCHEMBL27896825 | 0.81 | KMO (0.64) | KMODHODHHDAC8RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134848-B | Multicomponent polyaramide and its preparation method and use | 中国科学院化学研究所 | 2020-09-18 | — | — | CN | disclosed |