Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.55 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453166 | 0.98 | KMO (0.55) | DHODHKMOHDAC8EGFRRXRA | |
| SCHEMBL12070646 | 0.95 | KMO (0.57) | DHODHKMOHDAC8EGFRRXRA | |
| SCHEMBL27843569 | 0.91 | KMO (0.56) | DHODHKMOHDAC8RXRARXRB | |
| SCHEMBL8060297 | 0.85 | ALDH1A1 (0.36) | DHODHKMORXRARXRBATM | |
| SCHEMBL30698052 | 0.84 | KMO (0.67) | DHODHKMOHDAC8RXRARXRB | |
| SCHEMBL699008 | 0.84 | KMO (0.67) | DHODHKMOHDAC8RXRARXRB | |
| SCHEMBL22064857 | 0.84 | EGFR (0.60) | DHODHKMOEGFRRXRARXRB | |
| Biphenyl SCHEMBL505047 | 0.83 | RAB9A (0.52) | KMOHDAC8MAPTSMN1; SMN2TDP1 | |
| Hydrogen Sulfide SCHEMBL27896825 | 0.83 | KMO (0.64) | DHODHKMOHDAC8RXRARXRB | |
| Benzene SCHEMBL28576976 | 0.83 | TDP1 (0.43) | MAPTATMTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4999411-A | Polythioethers, polythiocarbonates, polythioamides, polythioimides | RAYCHEM LIMITED (GB) | 1991-03-12 | — | — | US | disclosed |
| US-4960835-A | ENGINEERING THERMOPLASTICS | RAYCHEM LIMITED (GB) | 1990-10-02 | — | — | US | disclosed |
| US-4845179-A | CONDENSATION POLYMERIZATION | RAYCHEM LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0154506-A2 | Preparation of organic polymers | RAYCHEM LIMITED (GB) | 1985-09-11 | — | — | EP | disclosed |