Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602832 | 0.76 | ESR2 (0.50) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL2914480 | 0.76 | MAPT (0.46) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1092954 | 0.71 | MPO (0.56) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11812180 | 0.69 | ILK (0.48) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1149953 | 0.69 | MPO (0.36) | LMNAKDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11752400 | 0.68 | LMNA (0.41) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3635540 | 0.66 | MAPT (0.39) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10371646 | 0.65 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL11749092 | 0.64 | ALDH1A1 (0.42) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2930623 | 0.63 | HPGD (0.48) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620865-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |